There are a number of ways to apply for Permanent Residence (commonly referred to as a Green Card) through employment sponsored immigration. There are even options for permanent residence without needing an employer sponsor (e.g. an individual that is extraordinary in their field). However, if you do not fall under that category, you will need to first determine which permanent resident category you fall under, and determine if you, and your sponsor employer, have the qualifications to have a successful application.
The U.S. Immigrant EB-3 Visa is generally a work visa as issued for foreign professionals when there is no American available for the role. The main categories are: EB-3 Skilled Workers / Professionals / Unskilled Workers (Other Workers) Green Card (including Schedule A Nurses and Physical Therapists)
